Monday, June 20, 2016

Effect of Non-Invasive Ventilation through Helmet Mask Vs Endotracheal Intubation

A recent randomized trial published in JAMA showed statistical significant decrease of endotracheal intubation in I.C.U patients with ARDS.

Total study population was 83 patients, with 45% being female and median APACHE II score 26. Among its results the study showed:


  • 43.3% difference in endotracheal intubation between mask group and helmet group, P<0.001)
  • increased ventilator-free days between the 2 groups (28 vs 12.5, P<0.001)
  • decreased mortality between the 2 groups (22.3% difference, P: 0.02)
The helmet's adverse events were confined to 6.8% neck ulcers.

Source: JAMA , clinicaltrials.gov

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